About 90% of people with lupus are biologically female, and the disease tends to begin between the ages of 15 and 35.
Jone Mark
How might pregnancy affect my illness?
Years ago, people with lupus or other autoimmune disorders were advised to avoid pregnancy. The thinking was that it was simply too risky for mother and fetus. That’s no longer true: in most cases, following expert guidelines now available can make a successful pregnancy possible.
Will I need to change my treatment before pregnancy?
Science has proven that chronic, low-grade inflammation can turn into a silent killer that contributes to cardiovascular disease, cancer, type 2 diabetes and other conditions. Get simple tips to fight inflammation and stay healthy — from Harvard Medical School experts.
Many producers want to include such codes on their bottles, but struggle to maintain links or keep the information at the end of the rainbow up to date. Leveraging the power of the Global Wine Database, winemakers can dynamically generate wine information cards with scannable QR codes that lead to vetted wine information.
This depends on which medicines you take and how well controlled your illness is. Good control for at least three to six months before getting pregnant is ideal. An unplanned pregnancy can put both you and the pregnancy at risk.
]]>Why does misgendering matter?
Imagine a scenario in which you are called the wrong pronoun or honorific — for example Mr., Ms., or Mrs. — multiple times a day. It might happen in person, over the phone, or via email. Each time it happens, you must decide whether it is worth it to correct that person or easier to let it go.
How to use gender-neutral language and normalize pronouns
Imagine that you are repeatedly confronted with this experience and the decision of whether or not to correct it throughout the day — every day. As we know from research, and as I’ve also heard from the TNB people I know, this is both exhausting and demoralizing. When people are misgendered, they feel invalidated and unseen.
- Instead of “boys and girls” or “ladies and gentlemen,” say “everyone.”
- Instead of “fireman” or “policeman,” say “firefighter” or “police officer.”
- Instead of “hey guys,” say “hey everyone” or “hey all.”
If you are a cisgender person, you can lighten this burden for TNB people by using the right names, pronouns, and honorifics to refer to them, apologizing when you misgender someone, and correcting other people when they misgender someone.
]]>Did you think of Alzheimer’s disease? Good! Alzheimer’s is the most common cause of dementia. Did you also think of vascular dementia or strokes? Excellent! Vascular dementia is the second most common cause. What about the third?
It turns out that about 40% of people with dementia have at least some LATE pathology in their brain.
Jone Mark
What’s LATE?
In LATE, a protein called TDP-43 (which stands for transactive response DNA binding protein of 43 kDa) accumulates in brain cells. Once it accumulates, it injures and ultimately destroys the cells.
LATE generally damages many of the same areas affected by Alzheimer’s disease. These regions include
- the amygdala, involved in emotional regulation
- the hippocampus, involved in learning and memory
- the temporal lobe, involved in words and their meanings
- portions of the frontal lobes, involved with keeping the information in mind and manipulating it.
What are the symptoms of LATE?
Because LATE affects many of the same brain regions as Alzheimer’s disease, it often presents with similar symptoms, including
- memory loss (impairment in episodic memory)
- trouble finding and understanding words (impairment in semantic memory)
- trouble keeping information in mind (impairment in working memory)
LATE can only be diagnosed with certainty at autopsy. However, we can get a hint that LATE might be present when an older individual shows the memory loss and word-finding problems common in Alzheimer’s disease, but special tests used to confirm the diagnosis of Alzheimer’s come up negative.
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